In order to compare the effect of 10% pentastarch solution with Ringer's lactate solution on plasma volume expansion in thirty epidural epidural anesthetic patients, systolic arterial blood pressure(SABP), diastolic arterial blood pressure(DABP),
heart
rate(HR), central venous pressure(CVP), cardiac output(CO) and changes of hemoglobin(Hb) were measured.
The patients were devided into three groups
Group I (n=10): Epidural anesthesia was performed without fluid infusion previously(control)
Group II(n=10); 500mg of Ringer's lactate solution was rapid infused intravenously before epidural anesthesia.
Group III (n=10); 500ml of 10% pentastarch solution was rapid infused intravenously before epidural anesthesia.
All data were collected before fluid infusion, at 15 min, at 30 min, at 45 min, at 60 min, at 120 min and at 180 min after epidural local anesthetic injection.
@ES The results are as follows.
@EN 1. SABP, DABP, HR, CVP and CO were decreased significantly (p<0.05) at 30, 45 minute after local epidural anesthetic injection in Group I and Group II. There was no any significant differences between two groups.
2. SABP, DABP, HR and CO were changed significantly, Besides CVP was increased significantly (p<0.05) after 10% pentastarch solution infusion in group III.
3. Changes of Hb were increased in group III.
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